LifeLiver® is a bioartificial liver support system classified as a state-of-the-art combination therapeutic of a cell therapy and a medical device.
Patients with 2 or3 grade of liver transplantation emergencies who need urgent liver transplantation due to acute or acute-on-chronic liver failure. (patients with a MELD score of 31 to 40)
Two-week mortality of 2- or 3-grade liver transplant emergency is close to 50%.
To remove the elevated blood ammonia, bilirubin, drugs, toxic metabolites and so on due to liver failure while waiting for liver transplantation.
To support the liver function, prolong the patient's life, by acting as a bridge.
LifeLiver® is administered in a way that circulates the patient's plasma outside of the body, as like kidney dialysis, and aids the liver function by recirculating the patient's plasma to a bioreactor filled with an amount of high-functioning hepatocyte spheroids.